Increases diagnostic accuracy while lowering production costs and improving patient comfort
This urinary test uses silicon nanoparticles suspended in a polymer to identify chronic lung diseases, including tuberculosis and lung cancer. Tuberculosis (TB), one of the world’s deadliest diseases, infected approximately 9 million people across the globe in 2011. Lung cancer is the most prevalent cancer among men worldwide and the second-most-prevalent cancer among women (after breast cancer). The United States spends approximately $154 billion a year on chronic lung disease care. Available techniques for diagnosing chronic lung disease include costly scans that cannot be performed in developing countries, or tests that require invasive sputum samples that cause patient discomfort. These diagnostics often miss less-advanced cases, delaying treatment. Inexpensive tests that detect early-stage disease and allow for prompt, life-saving medical interventions are in high demand. This diagnostic urine test developed by University of Florida researchers requires patients to inhale a small amount of dry powder. In the presence of chronic lung disease, the powder quickly breaks down, causing fluorescent silicon to be excreted in the urine within hours. The body safely eliminates the nontoxic powder over time.
ApplicationNon-invasive diagnostic for identifying chronic pulmonary diseases
- Eliminates false positives, reducing the number of misdiagnoses
- Utilizes readily available starting materials, widening the potential market to include developing countries
- Provides results in just a few hours, alleviating patients' anxiety