Monoclonal Antibody Against CUGBP2/ETR-3 Proteins 

Technology #11977

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Researchers
Maurice Scott Swanson
Managed By
John Byatt
Assistant Director 352-392-8929

Scientists at the University of Florida have developed a wide variety of monoclonal and polyclonal antibodies, cell lines, vectors and biological materials that can be used in other research projects. Anyone interested in accessing these materials via a license from the University of Florida should contact our office to make arrangements. CUGBP2/ETR-3 is member of the CELF family of pre-mRNA alternative splicing factors which play an important role in the appearance of specific protein isoforms during postnatal development. The CELF family has also been implicated in the neuromuscular disease myotonic dystrophy. The monoclonal antibody was generated against a purified human CUGBP2/ETR-3 protein fragment fused to GST and recognizes both human and mouse CUGBP2/ETR-3 proteins (elav-type RNA-binding protein), but does not bind to other members of the CELF family. Journal article:http://onlinelibrary.wiley.com/doi/10.1002/dvdy.20382/abstract;jsessionid=C203091EB01A61DC4DBC604B10C9378B.d02t03 (Wiley Online Library subscription required)