Monoclonal Antibody Against Cholecystokinin (CCK) Receptor 2

Technology #11934

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Researchers
Martha Campbell-Thompson
Managed By
John Byatt
Assistant Director 352-392-8929

Targeting Proteins that Regulate Anxiety and Digestion

Scientists at the University of Florida have developed a wide variety of monoclonal and polyclonal antibodies, cell lines, vectors and biological materials that can be used in other research projects. Anyone interested in accessing these materials via a license from the University of Florida should contact our office to make arrangements.This antibody was generated against recombinant rat CCKB receptor. The antibody cross-reacts with mouse CCK2 as well as the human homolog (92% amino acid similarity) and has been used to show positive immuno-reactivity to cortical neurons via immunohistochemistry. CCK2 is a receptor that helps regulate anxiety, digestion, and locomotion. This antibody is expected to be useful for studies in the central nervous system, gastrointestinal tract and other organs.