Monoclonal Antibody Against Human Calcium-Sensing Receptor 

Technology #11931

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Researchers
R. Tyler Miller M.D.
Managed By
John Byatt
Assistant Director 352-392-8929

Targeting Receptor that Regulates Calcium Levels in Cells

Scientists at the University of Florida have developed a wide variety of monoclonal and polyclonal antibodies, cell lines, vectors and biological materials that can be used in other research projects. Anyone interested in accessing these materials via a license from the University of Florida should contact our office to make arrangements. Mouse monoclonal antibody directed against the extracellular N-terminus of the human calcium-sensing receptor. The calcium sensing receptor detects extracellular levels of calcium to determine the intake levels of calcium for cells. The antibody was generated against a synthetic peptide (SSAYGPDQRAQKK) corresponding to amino acids 15 - 29 in the extracellular amino terminus of human CaR. The antibody recognizes human, mouse, rat, and rabbit proteins. Journal article: http://www.jbc.org/content/276/37/34871.long