Monoclonal Antibodies Against Limulus Visual Arrestin

Technology #11731

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Researchers
Barbara-Anne Battelle
Wesley Clay Smith Ph.D
Managed By
John Byatt
Assistant Director 352-392-8929

Targeting Proteins that May Cause Eye Disease

Scientists at the University of Florida have developed a wide variety of monoclonal and polyclonal antibodies, cell lines, vectors and biological materials that can be used in other research projects. Anyone interested in accessing these materials via a license from the University of Florida should contact our office to make arrangements. This MAb (4 different hybridomas) is raised against the N-terminal half of recombinant Limulus (horseshoe crab) visual arrestin, which is a protein that interrupts light-activated signal transduction in the eye, causing an autoimmune eye disorder. Antibodies are specific for Limulus- wide species; cross-reactivity was not tested. Journal articles: ‘http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=62113 (Cambridge Journals subscription required) http://onlinelibrary.wiley.com/doi/10.1002/cne.10263/full (Wiley Online Library subscription required)